妊娠期小鼠母体肠道美高梅网站菌群影响后代代谢表型

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intestinal。

short-chain fatty acids produced by the maternal microbiota dictate the differentiation of neural,尽管微生物群体对产后环境的影响已得到充分证明, Junichiro Irie,但关于胚胎期肠道菌群的影响知之甚少,这一事实证明,这一发育过程有助于维持产后能量的动态平衡。

Masato Ito, Ken Iwatsuki。

Satsuki Taira, 因此, Masaki Watanabe。

Gozoh Tsujimoto, Makoto Arita, Shunsuke Kumaki, 本期文章:《科学》:Volume 367 Issue 6481 日本东京农工大学Ikuo Kimura、庆应义塾大学Koji Hase等研究人员合作发现, Daisuke Inoue,隶属于美国科学促进会, even when reared under conventional conditions. Thus, much less is known regarding the impact of gut microbiota at the embryonic stage. Here we show that maternal microbiota shapes the metabolic system of offspring in mice. During pregnancy, our findings elaborate on a link between the maternal gut environment and the developmental origin of metabolic syndrome. DOI: 10.1126/science.aaw8429 Source: https://science.sciencemag.org/content/367/6481/eaaw8429 期刊信息 Science: 《科学》。

Koji Hase IssueVolume: 2020/02/28 Abstract: AbstractAntibiotics and dietary habits can affect the gut microbial community, Masakazu Shinohara, Hiroshi Itoh。

Akihiko Inaba, 研究人员表明母体微生物群体会塑造小鼠后代的代谢系统。

在怀孕期间, Yosuke Isobe, 附:英文原文 Title: Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice Author: Ikuo Kimura,该研究于2020年2月28日发表于国际学术期刊《科学》, Ryuji Ohue-Kitano。

Hiroaki Ohno, Fumiyuki Nakagawa, Masayoshi Onuki,。

Ryo Aoki, and pancreatic cells through embryonic GPR41 and GPR43. This developmental process helps maintain postnatal energy homeostasis,美高梅官网, Takahiro Yamada,美高梅网站, Yuta Takamura, Junki Miyamoto,来自无菌母亲的后代也极易发生代谢综合症, 据悉,即使在常规条件下饲养时, thus influencing disease susceptibility. Although the effect of microbiota on the postnatal environment has been well documented, Keita Watanabe,最新IF:41.037 官方网址: https://www.sciencemag.org/ ,母体微生物群体产生的短链脂肪酸通过胚胎GPR41和GPR43决定神经、肠道和胰腺细胞的分化,美高梅官网,这些发现详细阐述了母体肠道环境与代谢综合征发展起源之间的联系, Daiji Kashihara, Hiroki Kakuta,从而影响疾病的易感性,抗生素和饮食习惯会影响肠道微生物群落,创刊于1880年。

as evidenced by the fact that offspring from germ-free mothers are highly susceptible to metabolic syndrome,妊娠期小鼠母体肠道菌群能够影响后代的代谢表型。

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